One Pot Synthesis of α-Aminophosphonates Containing Bromo and 3,4,5-Trimethoxybenzyl Groups under Solvent-free Conditions

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One pot synthesis of alpha-aminophosphonates containing bromo and 3,4,5-trimethoxybenzyl groups under solvent-free conditions.

New alpha-aminophosphonates were synthesized by the Kabachnik-Fields reaction of 3,4,5-trimethoxybenzaldehyde (TMB) with p- or m-bromoaniline and a dialkyl phosphite under solvent-free conditions. TMB was prepared from gallic acid via a four step synthetic sequence involving etherification, esterification, hydrazidation and potassium ferricyanide oxidation. The structures of all synthesized com...

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Green and Efficient One-Pot Synthesis of 2-Amino-3-phenylsulphonyl-4H-chromenes under Solvent-Free Conditions

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ژورنال

عنوان ژورنال: Molecules

سال: 2007

ISSN: 1420-3049

DOI: 10.3390/12020163